Cognome - Nome |
MALISAN Florence |
Posizione |
Professore Associato |
Telefono |
+39 06 7259 6504 |
S.S.D. |
MED/46 - Scienze Tecniche di Medicina di Laboratorio |
S.C. |
06/N1- Scienze delle Professioni Sanitarie e delle Tecnologie Mediche Applicate |
e-mail |
|
Interessi di Ricerca |
• Immunologia • Atassia di Friedreich • Biomarcatori • Epigenetica - miRNA • Apoptosi |
ATTIVITÀ DI RICERCA
L'esperienza della Prof.ssa Florence Malisan (ID ORCID 0000-0002-0213-9407) nella biologia molecolare e biochimica abbraccia una vasta gamma di aree, tra cui biologia molecolare, biologia cellulare, biologia dei glicolipidi, trasfezione cellulare, espressione genica, proteomica, analisi proteica e rilevamento mediante western blot, citometria a flusso, immunofluorescenza, ELISA.
Negli ultimi 15 anni ha studiato il ruolo della proteina frataxina nella malattia genetica dell'atassia di Friedreich (FRDA). Sia la patofisiologia molecolare che nuovi approcci terapeutici sono oggetto di indagine (http://www.labst.org).
EDUCAZIONE
• 1996: Dottorato in Immunologia : "Molecular and cellular studies of in vivo and in vitro isotype switch by human B lymphocytes"; sotto la direzione del Dr. J. Banchereau, Schering-Plough, Dardilly, France
Votazione: “Molto onorevole con lodi” concessa all’unanimità e riservata al 10% delle migliori
tesi dell’Université Claude Bernard, Lyon I, France.
• 1992: Diplôme d'Etudes Approfondies (DEA = Master 2, Laurea Magistrale) de Différenciation, Génétique et Immunologie. Université Claude Bernard, Lyon I, France. France.
• 1987: Maturità (Baccalauréat ) at Annecy, France.
PREMI E RICONOSCIMENTI
• 1996-1998: Borsa post-dottorato Europea (EEC) Human Mobility Capital
• 1999-2001: Borsa post-dottorato Fondazione Italiana per la Ricerca sul Cancro (FIRC).
ESPERIENZA DI RICERCA
• 1992-1996 : PhD, Schering-Plough, France, under the direction of Drs J. Banchereau and
H. Martinez-Valdez: "Cellular and molecular biology on human B cells".
• 1993-1994: Visiting PhD student at Center for Biologics Evaluation and Research, Food and Drug
Administration, Bethesda, MD, USA, under the direction of Drs E.E. Max e F.C. Mills.
• 1998: Visiting researcher at Department of Molecular Toxicology, Faculty of Biology,
University of Konstanz, Germany, under the direction of Prof. P. Nicotera.
• 2002-2005: Research Associate: Department of Experimental Medicine
and Biochemical Sciences, University of Rome Tor Vergata.
• 2006-2017: Ricercatore (MED/04), Department of Biomedicine
and Prevention, University of Rome Tor Vergata
BREVETTI
Methods of treating Friedreich’s ataxia using Src inhibitors, assigned serial no. PCT/IB2015/059963, published 30 June 2016, n. WO2016103223 A1.
DIDATTICA
Insegna Immunologia in diversi corsi di Laurea come Medicina e Chirurgia (dal 2006 in Italiano e 2013 in Inglese), Pharmacy (dal 2009), Tecniche di Laboratorio Biomedico and Dietistica (dal 2018) per un totale di 15 CFU con circa 110 ore di didattica frontale (oltre 250 studenti e 21 sessioni di esami/anno).
PUBBLICAZIONI SCIENTIFICHE
https://pubmed.ncbi.nlm.nih.gov/?term=malisan+f
Link SCOPUS profile:
https://www.scopus.com/authid/detail.uri?authorId=6603006524
L'esperienza della Prof.ssa Florence Malisan (ID ORCID 0000-0002-0213-9407) nella biologia molecolare e biochimica abbraccia una vasta gamma di aree, tra cui biologia molecolare, biologia cellulare, biologia dei glicolipidi, trasfezione cellulare, espressione genica, proteomica, analisi proteica e rilevamento mediante western blot, citometria a flusso, immunofluorescenza, ELISA.
Negli ultimi 15 anni ha studiato il ruolo della proteina frataxina nella malattia genetica dell'atassia di Friedreich (FRDA). Sia la patofisiologia molecolare che nuovi approcci terapeutici sono oggetto di indagine (http://www.labst.org).
EDUCAZIONE
• 1996: Dottorato in Immunologia : "Molecular and cellular studies of in vivo and in vitro isotype switch by human B lymphocytes"; sotto la direzione del Dr. J. Banchereau, Schering-Plough, Dardilly, France
Votazione: “Molto onorevole con lodi” concessa all’unanimità e riservata al 10% delle migliori
tesi dell’Université Claude Bernard, Lyon I, France.
• 1992: Diplôme d'Etudes Approfondies (DEA = Master 2, Laurea Magistrale) de Différenciation, Génétique et Immunologie. Université Claude Bernard, Lyon I, France. France.
• 1987: Maturità (Baccalauréat ) at Annecy, France.
PREMI E RICONOSCIMENTI
• 1996-1998: Borsa post-dottorato Europea (EEC) Human Mobility Capital
• 1999-2001: Borsa post-dottorato Fondazione Italiana per la Ricerca sul Cancro (FIRC).
ESPERIENZA DI RICERCA
• 1992-1996 : PhD, Schering-Plough, France, under the direction of Drs J. Banchereau and
H. Martinez-Valdez: "Cellular and molecular biology on human B cells".
• 1993-1994: Visiting PhD student at Center for Biologics Evaluation and Research, Food and Drug
Administration, Bethesda, MD, USA, under the direction of Drs E.E. Max e F.C. Mills.
• 1998: Visiting researcher at Department of Molecular Toxicology, Faculty of Biology,
University of Konstanz, Germany, under the direction of Prof. P. Nicotera.
• 2002-2005: Research Associate: Department of Experimental Medicine
and Biochemical Sciences, University of Rome Tor Vergata.
• 2006-2017: Ricercatore (MED/04), Department of Biomedicine
and Prevention, University of Rome Tor Vergata
BREVETTI
Methods of treating Friedreich’s ataxia using Src inhibitors, assigned serial no. PCT/IB2015/059963, published 30 June 2016, n. WO2016103223 A1.
DIDATTICA
Insegna Immunologia in diversi corsi di Laurea come Medicina e Chirurgia (dal 2006 in Italiano e 2013 in Inglese), Pharmacy (dal 2009), Tecniche di Laboratorio Biomedico and Dietistica (dal 2018) per un totale di 15 CFU con circa 110 ore di didattica frontale (oltre 250 studenti e 21 sessioni di esami/anno).
PUBBLICAZIONI SCIENTIFICHE
https://pubmed.ncbi.nlm.nih.gov/?term=malisan+f
Link SCOPUS profile:
https://www.scopus.com/authid/detail.uri?authorId=6603006524
Family Name- Name |
MALISAN Florence |
Position |
Associate Professor |
Telefono |
+39 06 7259 6204 |
S.S.D. |
MED/46 - Medical and Biotechnology Laboratory Techniques |
S.C. |
06/N1 - Applied Medical Technologies |
e-mail |
RESEARCH ACTIVITY
The expertise of Prof. Florence Malisan (ORCID ID 0000-0002-0213-9407) in molecular and biochemical biology encompasses a wide range of areas including molecular biology, cell biology, glycolipid biology, cell transfection, in vitro gene delivery, gene expression, proteomics, protein analysis and detection by western blot, flow cytometry, immunofluorescence, ELISA.
During the last 15 years she studied the role of the frataxin protein in the genetic disease Friedreich’s ataxia (FRDA). Both molecular pathophysiology and novel therapeutic approaches are under investigation (http://www.labst.org).
EDUCATION
• 1996: PhD in Immunology, with highest Honour -awarded to 10% of the best theses- at the University Claude Bernard of Lyon, in France.
• 1992: Degree in Biological Sciences (Master 2) at the University Claude Bernard of Lyon, in France.
• 1987: High School Diploma in Sciences at Annecy, France.
AWARDED FELLOWSHIPS
• 1996-1998: EEC Human Mobility Capital postdoctoral fellowship
• 1999-2001: Postdoctoral Research fellowship from Italian Foundation for Cancer Research (FIRC).
RESEARCH EXPERIENCE
• 1992-1996 : PhD, Schering-Plough, France, under the direction of Drs J. Banchereau and
H. Martinez-Valdez: "Cellular and molecular biology on human B cells".
• 1993-1994: Visiting PhD student at Center for Biologics Evaluation and Research, Food and Drug
Administration, Bethesda, MD, USA, under the direction of Drs E.E. Max e F.C. Mills.
• 1998: Visiting researcher at Department of Molecular Toxicology, Faculty of Biology,
University of Konstanz, Germany, under the direction of Prof. P. Nicotera.
• 2002-2005: Research Associate: Department of Experimental Medicine
and Biochemical Sciences, University of Rome Tor Vergata.
• 2006-2017: Researcher - Assistant Professor (MED/04), Department of Biomedicine
and Prevention, University of Rome Tor Vergata
PATENTS
Methods of treating Friedreich’s ataxia using Src inhibitors, assigned serial no. PCT/IB2015/059963, published 30 June 2016, n. WO2016103223 A1.
TEACHING
She is in charge of Immunology courses in Degree course in Medicine and Surgery (since 2006 in Italian and 2013 in English), Pharmacy (since 2009), Biomedical Laboratory Techniques and Dietetics (since 2018) for a total of 15 ECTS Credits with 110 hours of lectures (more than 250 students and 21 exam sessions/year).
SCIENTIFIC PUBLICATIONS
https://pubmed.ncbi.nlm.nih.gov/?term=malisan+f
Link SCOPUS profile:
https://www.scopus.com/authid/detail.uri?authorId=6603006524
The expertise of Prof. Florence Malisan (ORCID ID 0000-0002-0213-9407) in molecular and biochemical biology encompasses a wide range of areas including molecular biology, cell biology, glycolipid biology, cell transfection, in vitro gene delivery, gene expression, proteomics, protein analysis and detection by western blot, flow cytometry, immunofluorescence, ELISA.
During the last 15 years she studied the role of the frataxin protein in the genetic disease Friedreich’s ataxia (FRDA). Both molecular pathophysiology and novel therapeutic approaches are under investigation (http://www.labst.org).
EDUCATION
• 1996: PhD in Immunology, with highest Honour -awarded to 10% of the best theses- at the University Claude Bernard of Lyon, in France.
• 1992: Degree in Biological Sciences (Master 2) at the University Claude Bernard of Lyon, in France.
• 1987: High School Diploma in Sciences at Annecy, France.
AWARDED FELLOWSHIPS
• 1996-1998: EEC Human Mobility Capital postdoctoral fellowship
• 1999-2001: Postdoctoral Research fellowship from Italian Foundation for Cancer Research (FIRC).
RESEARCH EXPERIENCE
• 1992-1996 : PhD, Schering-Plough, France, under the direction of Drs J. Banchereau and
H. Martinez-Valdez: "Cellular and molecular biology on human B cells".
• 1993-1994: Visiting PhD student at Center for Biologics Evaluation and Research, Food and Drug
Administration, Bethesda, MD, USA, under the direction of Drs E.E. Max e F.C. Mills.
• 1998: Visiting researcher at Department of Molecular Toxicology, Faculty of Biology,
University of Konstanz, Germany, under the direction of Prof. P. Nicotera.
• 2002-2005: Research Associate: Department of Experimental Medicine
and Biochemical Sciences, University of Rome Tor Vergata.
• 2006-2017: Researcher - Assistant Professor (MED/04), Department of Biomedicine
and Prevention, University of Rome Tor Vergata
PATENTS
Methods of treating Friedreich’s ataxia using Src inhibitors, assigned serial no. PCT/IB2015/059963, published 30 June 2016, n. WO2016103223 A1.
TEACHING
She is in charge of Immunology courses in Degree course in Medicine and Surgery (since 2006 in Italian and 2013 in English), Pharmacy (since 2009), Biomedical Laboratory Techniques and Dietetics (since 2018) for a total of 15 ECTS Credits with 110 hours of lectures (more than 250 students and 21 exam sessions/year).
SCIENTIFIC PUBLICATIONS
https://pubmed.ncbi.nlm.nih.gov/?term=malisan+f
Link SCOPUS profile:
https://www.scopus.com/authid/detail.uri?authorId=6603006524
|
Dipartimento di Biomedicina e Prevenzione
Department Biomedicine and Prevention Facoltà di Medicine e Chirurgia Faculty of Medicine and Surgery Università di Roma Tor Vergata University of Rome Tor Vergata Indirizzo/Address: Viale Montpellier, 1 – Roma (Studio D12) |
Direttore del Dipartimento / Director of the Department Prof. Antonio De Lorenzo Responsabile Amministrativo / Administrative Head Avv. Ombretta Picchioni Content manager del sito / Content manager of the website Prof. Andrea Malizia |