RICERCATORE

e-mail: campagnolo@med.uniroma2.it
Telefono: +39 06 7259 6154/51 
SSD: BIO/17
SC: 05/H2 
Macro-area:
Istologia
Campi di interesse: 
06/72596154
-Meccanismi molecolari dello sviluppo placenta
-Cellule Staminali
-Nanoparticelle e embriotossicità

 Dr. Luisa Campagnolo

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CURRICULUM VITAE
 
Dr. Campagnolo has a broad background in reproductive and developmental biology, in histology and in vascular and stem cell biology. Research in her lab has been supported by grants from the European Community, the Italian Ministry of Health and the  March of Dimes. Dr Campagnolo has been the Italian Representative in the Management Committee of the EU COST Action MODENA TD1204 and has been recently nominated Italian Representative in the OECD Working Party on Manufactured Nanomaterials.
The main research focus in the Campagnolo’s lab is to examine the molecular mechanisms regulating mammalian embryo implantation and placental development. Over the last 5 years Dr Campagnolo has also developed a new research focus on toxicological aspects of engineered nanomaterials (ENM) and placental/fetal susceptibility, which is strictly related to her main interests.  Altogether, these studies has allowed Dr Campagnolo to establish strong collaborations with national and international research groups. The laboratory of Dr. Campagnolo possesses expertise on the handling and culture of pre- and post-implantation embryos, culture of stem cells of different sources (embryonic, adult, induced), morphological, biochemical, histological and molecular biology techniques. Three main research lines are currently followed in the laboratory: 1. Examine the role of Egfl7 during placental development.  This project is performed in collaboration with Dr Stuhlmann at the Weill Cornell Medical College in New York, and is supported by a pilot study grant from the March of Dimes Foundation (2014-2017), of which Dr Campagnolo is a subcontractor. 2. Investigate the role of thyroid hormone in mammalian embryo implantation. This studies are performed in collaboration with Prof Moretti, and Prof Ulisse of the University of Rome “La Sapienza” 3. Study the effect of maternal exposure to ENM on placental and fetal evelopment, and on the second generation; develop in vitro tests to evaluate transplacental passage of ENM.
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Positions and Employment
1995-1999           Graduate student of Medical Embryology, Dep of Public Health and cell Biology, University of Rome “Tor Vergata”, Rome, Italy.
1999-2000           Postdoctoral fellow , Dep of Public Health and cell Biology, University of Rome “Tor Vergata”, Rome, Italy.
2000-2003           Postdoctoral fellow, Dep Cell Biology, The Scripps Research Institute, La Jolla, CA
2002-                    Assistant Professor, Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Rome, Italy.

Other Experience and Professional Memberships
2001-2014           Member, North American Vascular Biology Organization (NAVBO)
2014-                    Member, European Society of Human Reproduction and Embryology
 
2011-                   Editorial Board, International Journal of Stem Cell & Transplantation
2013-                   Editorial Board, Particle and Fibre Toxicology
 
2010                     Ad Hoc Reviewer, Kentucky Science & Engineering Foundation
2010                    Ad Hoc Reviewer, Medical Research Scotland
2015                     Ad Hoc Reviewer, Italian Ministry of Instruction, University and Research
2016                     Expert Reviewer, OPUS call of the National Science Centre, Poland
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Honors
2001                     “Servier New Investigator Award” 2nd Conference on Artheriosclerosis, Thrombosis and Vascular Biology (Washington DC)
2007-present      Visiting Assistant Professor, Weill Cornell Medical College, New York, USA
2009:                   Award Best Presentation, AIPE Meeting, Rome, ITALY
2010:                   Award Best Poster,  Nanotoxicology Meeting, Edinburgh, UK.
2015                     Invited Plenary Lecturer, Karolinska Institutet, Stockholm, Sweden
2016                     Invited Speaker, Society of Toxicology Meeting 2016, New Orleans, USA
2016                     Invited Speaker, IUTOX Meeting 2016, Merida, Mexico
2016-present     Research Associate, Dept. of Chemical Engineering, University of Pretoria

Pubblicazioni rilevanti

• Campagnolo L, Telesca C, Massimiani M, Stuhlmann H, Angelico M, Lenci I, Manzia TM, Tariciotti L, Lehmann G, Baiocchi L. Different expression of VEGF and EGFL7 in human hepatocellular carcinoma. Dig Liver Dis. 2016 Jan;48(1):76-80. doi: 10.1016/j.dld.2015.09.019. PubMed PMID: 26542361.
• Colicchia M, Campagnolo L, Baldini E, Ulisse S, Valensise H, Moretti C. Molecular basis of thyrotropin and thyroid hormone action during implantation and early development. Hum Reprod Update. 2014 Nov-Dec;20(6):884-904. doi: 10.1093/humupd/dmu028. Review. PubMed PMID: 24943836.
• Massimiani M, Vecchione L, Piccirilli D, Spitalieri P, Amati F, Salvi S, Ferrazzani S, Stuhlmann H, Campagnolo L. Epidermal growth factor-like domain 7 promotes migration and invasion of human trophoblast cells through activation of  MAPK, PI3K and NOTCH signaling pathways. Mol Hum Reprod. 2015 May;21(5):435-51. doi: 10.1093/molehr/gav006. PubMed PMID: 25667199; PubMed Central PMCID: PMC4492406.
• Campagnolo L, Massimiani M, Palmieri G, Bernardini R, Sacchetti C, Bergamaschi A, Vecchione L, Magrini A, Bottini M, Pietroiusti A. Biodistribution and toxicity of pegylated single wall carbon nanotubes in pregnant mice. Part Fibre Toxicol. 2013 Jun 6;10:21. doi: 10.1186/1743-8977-10-21. PubMed PMID: 23742083; PubMed Central PMCID: PMC3679973.
• Campagnolo L, Fenoglio I, Massimiani M, Magrini A, Pietroiusti A. Screening of nanoparticle embryotoxicity using embryonic stem cells. Methods Mol Biol. 2013;1058:49-60. doi: 10.1007/7651_2013_11. PubMed PMID: 23592031.